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Otezla (apremilast) is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) to treat adults with active psoriatic arthritis. Otezla is a pill taken by mouth.

Common Otezla Side Effects include:

• diarrhea

• nausea

• upper respiratory tract infection

• headache

• depression

• itching

• runny nose

• fatigue

• sore throat

Tell your doctor if you have any side effect that bothers you or does not go away. These are not all the possible Otezla Side Effects. For more information, ask your doctor or pharmacist.